CASE SUBMISSION GUIDELINES
The workshop panel will collate and discuss all cases submitted to the Workshop. All cases will be organized into eight sessions using the topics chosen by the submitter in the online system but may be rescheduled at the discretion of the Workshop Panel. Approximately 40 cases (4 or 5 cases per session) will be presented during the meeting. Early submissions are strongly encouraged.
Case Topics
- The focus of the 2025 Workshop is pediatric hematopathology. Cases will be accepted for patients aged 25 years or younger. Other than where stipulated below, cutaneous lymphomas will not be considered.
- Myeloid and Precursor Lymphoid Neoplasms
- Acute myeloid leukemias (AMLs) and acute lymphoblastic leukemias (ALLs) representing new diagnostic entities in the WHO-5 or ICC classifications
- AML of infants/toddlers, including Down syndrome-associated myeloid leukemia/TAM, AMKL, and/or those with rearrangements of KMT2A, NUP98, or ETV6
- Myeloproliferative neoplasms in the pediatric setting and their mimics
- Juvenile myelomonocytic leukemia and its benign and neoplastic mimics (JMML-like neoplasms)
- Pediatric MDS and other myeloid malignancies developing in the setting of germline predisposition syndromes
- Myeloid sarcoma
- B-cell Lymphomas
- High-grade/large B-cell lymphomas other than Burkitt lymphoma, including DLBCL with IRF4 rearrangement, cases with 11q aberrations, DLBCL/high-grade lymphoma with MYC and BCL2 rearrangements
- Challenging B-cell lymphomas with mediastinal presentations, including primary mediastinal large B-cell lymphoma, grey zone lymphoma, and classic Hodgkin lymphoma
- Indolent B-cell lymphomas, including pediatric-type follicular lymphoma and pediatric nodal marginal zone lymphoma
- EBV Positive Lymphomas
- Severe mosquito bite allergy
- Hydroa vacciniforme lymphoproliferative disorder
- Systemic chronic active EBV infection
- Systemic EBV positive T-cell lymphoma of childhood
- EBV positive nodal and extranodal T-cell and NK-cell lymphomas
- EBV positive diffuse large B-cell lymphoma
- Reactive and Neoplastic Histiocytic Disorders
- Genetic (primary) HLH
- Challenging or unusual cases of secondary HLH
- Systemic chronic active EBV infection
- Florid histiocytic proliferations developing in association with a lymphoma that mimic a histiocytic neoplasm and mask the underlying lymphoma
- Langerhans cell histiocytosis
- Histiocytic neoplasms, including juvenile xanthogranuloma, Rosai-Dorfman disease, ALK-positive histiocytosis, histiocytic sarcoma
Case Submission Information
Please note the following guidelines for case submission. The online submission system will automatically enforce these guidelines:
- Case text is limited to 3,500 characters
- Please structure your case as follows:
- Clinical Information
- Description of Submitted Tissues, including fixative and decalcification method (if applicable)
- Details of Microscopic Findings
- Immunophenotype
- Cytogenetics
- Molecular Studies
- Proposed Diagnosis/ses
- Interesting Features of Case
- Molecular characterization will be performed as needed on select cases; submitters will be contacted directly where appropriate to submit either unstained slides or paraffin scrolls.
- Tissue Submission: Each case should include the submission of (1) one H&E slide of representative tissue per specimen. Submitters may be contacted directly, as needed, to submit additional unstained slides for immunohistochemical studies. The submitted H&E slide may also be made available to all workshop attendees in the form of digital whole slide imaging, if your case is selected for individual presentation.
- Please upload your slides (max. 10 MB, PowerPoint) using the provided template.
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- All cases must contain original work and content that has not been published in a peer-review journal.
- The case submission fee is 35 USD.
- Cases must be submitted in English. Please check spelling and grammar carefully.
